Chemistry Department

Dr. Sandra Misquith
Associate Professor
E - mail id: s.misquith@sjc.ac.in
Area: Chemistry
Affiliation: Department of chemistry
Qualification: M.Sc., Ph.D
Teaching Experience: 21 years 2 Months

EDUCATION

B.Sc Chemistry Honours, Physics, Mathematics St Xavier’s College, Calcutta
M.Sc. Biochemistry Ballygung Science College, Calcutta
Ph.D Chemistry Facultes Universitaires Notre Dame de la Paix(FUNDP), Namur, Belgium

Teaching/Research Interests
Teaching: Organic chemistry, general chemistry, analytical chemistry and biochemistry
Research: Enzymology, Lectin chemistry, Anti-coagulants

Projects

Project Title Funding agency Broad area of investigation Duration Amount sanctioned

Insights into the substrate specificity of nucleotide cyclases. Mutagenesis, biochemical and structural characterisation of the adenylyl cyclase Ma1120 of Mycobacterium avium

CSIR

Biochemistry and structural biology

3 years

Rs 2,600,000.00


Awards
1996 Young Scientist
DST
1996 Young Scientist
KAAS
2003 Commonwealth Academic Staff Fellowship
Commonwealth, UK

Invited Talks/ Lectures Given
2014 Understanding the structure of proteins and Nucleic Acids
Refresher Course for teachers
Christ University
2014 Enzyme substrate interactions
Refresher Course for teachers
Jain University
2010 Lectin from carica papaya specifically recognises the triantennary complex of fetuin
4th General assembly and International conference
OWSD, Beijing, China

Conferences Attended
June 2010 4th General Assembly and International Conference on Women Scinetists in a Changing world
TWOWS, Chinese academy of Science
Nov 2012 Symposium on Chemistry and Biology: Two weapons against diseases
Society of Biological Chemists, Kolkata
Nov 2015 14th FAOBMB Congress: Current excitements in Biochemistry and Molecular Biology for Agriculture and Medicine
IUBMB, FAOBMB, SBC, Hyderaba

Collaborations
Prof. Suguna, MBU, IISc, Bangalore Prof. S Visweswariah, MRDG, IISc, Bangalore Prof. B. Gopal, MBU, IISc, Bangalore Prof. J Wouters, Department of Chemistry, Univ of Namur, Belgium

Publications

Title of paper Authors Journal YOP Vol/Issue/ Page no.s

Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase

Barathy DV, Bharambe NG, Syed W, Zaveri A, Visweswariah SS, Colaςo M, Misquith S, Suguna K.

J Struct Biol.

2015

190/304-313

Mutational analysis gives insight into substrate preferences of a nucleotidyl cyclase from Mycobactericium avium

Syed W., Colaco M., Misquith S

PLoS One

2014

9/e109358

Structure of an amidohydrolase, SACOL0085, from methicillinresistant Staphylococcus aureus COL.

Girish TS, B V, Colaco M, Misquith S, Gopal B.

Acta Crystallogr Sect F Struct Biol Cryst Commun.

2013

69/103-108

A comparative study of the subcellular distribution of gelonin and deglycosylated gelonin in rat liver and kidney

Colaco, M., Misquith S, Bapat, M.M., Wattiaux-De Coninck S. Wattiaux R

Biochem. Biophy. Res Comm

2004

319/1299-1306

Exploring Enzyme amplification to characterise specificities of proteincarbohydrate recognition

Patil A. R., Misquith, S., Dam, T.K., Sharma, V., Kapoor, M., Surolia, A

Methods Enzymol

2003

362/567-583

Uptake and Intracellular fate of gelonin, a ribosome inactivating protein in rat liver

Colaco, M., Bapat, M.M., Misquith S, Jadot M, Wattiaux-De Coninck S. Wattiaux R

Biochem. Biophy. Res Comm

2002

296/1180-1185

Thermodynamic studies of saccharide binding to artocarpin, a B-cell mitogen, reveals the extended nature of its interaction with mannotriose [3,6-Di-O-(alpha -D-mannopyranosyl)-Dmannose]

Rani PG, Bachhawat K, Misquith S, Surolia A

J Biol Chem

1999

274 29694-8.

A cytolytic function for a sialic acid-binding lectin that is a member of the pentraxin family of proteins

Armstrong PB, Swarnakar S, Srimal S, Misquith S, Hahn EA, Aimes RT, Quigley JP

J Biol Chem

1996

271/14717-21

X-ray structure of gelonin at 1.8 A resolution

Hosur MV, Nair B, Satyamurthy P, Misquith S, Surolia A, Kannan KK

J Mol Biol.

1995

250.368-80

Carbohydrate binding specificity of the B-cell maturation mitogen from Artocarpus integrifolia seeds

Misquith S, Rani PG, Surolia A

J Biol Chem

1994

269/30393-401


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